7 Best Glucosamine Supplements for Dogs in 2025

Just like humans, dogs can experience joint discomfort due to age, wear and tear, or certain types of breeds being predisposed to joint issues. That’s where glucosamine supplements for dogs come in; they are a popular choice for pet owners looking to support their dog’s joint health. 

Dogs naturally produce glucosamine, and it’s a big part of why their joints stay flexible. Think of it as a cushion for their bones! By adding glucosamine to their diet, you can help keep their joints healthy and it may even soothe any stiffness or discomfort they might be experiencing.

Whether you have an active pup or a senior dog experiencing the aches of aging, you’d love to explore the top-rated glucosamine supplements listed below, carefully selected to help your dog move with ease and enjoy life to the fullest.

Does Glucosamine Work Immediately?

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If you’re considering glucosamine supplements for your dog, you may wonder how quickly you’ll see results. Here’s what to know:

Not an Instant Fix

Glucosamine doesn’t provide immediate relief. It’s a supplement, not a painkiller, and works gradually to repair cartilage and reduce inflammation.

Timeframe for Results

Most dogs show noticeable improvement in mobility and reduced stiffness within 4 to 6 weeks of consistent use.

Cumulative Benefits

The effects build over time. As glucosamine strengthens joint cartilage, the long-term benefits become more evident.

Depends on the Dog

Factors like age, breed, joint condition severity, and activity level affect how quickly glucosamine works for your pet.

Supplement and Beyond

For severe issues, glucosamine is often most effective when combined with a balanced diet, weight management, and vet-recommended therapies.

Note: Remember to follow dosage recommendations carefully. Refer to a “glucosamine for dogs” dosage chart or consult your vet to ensure optimal results!

The Best Glucosamine Supplements for Dogs in 2025

When you find the best glucosamine supplements for dogs, you essentially make sure your furry friend gets the support they need for healthy joints and improved mobility. You won’t have any trouble choosing from our top picks as they are good for dogs of all sizes and breeds and come in different forms, like chewable tablets and liquids.

Best Overall Best Soft Chews Best Plant-based Best for Small Breed Best for Senior Dogs Best Flavor Best Result

BEST OVERALL

Nutramax Laboratories Cosequin

Best Soft Chews

VetIQ Glucosamine Hip & Joint Supplement

BEST Best Plant-based

YuMOVE Hip and Joint Supplement

BEST FOR SMALL BREED

Wuffes Chewable Supplement

BEST FOR SENIOR DOGS

STRELLALAB Advanced Glucosamine

BEST FLAVOR

Zesty Paws Hip and Joint Supplement

BEST FAST RESULT

Pet Honesty Hip & Joint Health

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PHOTO CREDIT: AMAZON

Why We Love

Veterinarian recommended

Contains glucosamine, chondroitin, and MSM

Backed by science

Supports cartilage health

Tasty and easy to administer

Suitable for all sizes

But…

Requires several weeks of consistent use to show noticeable improvements

Cosequin is a top choice among veterinarians and a popular choice for pet owners seeking the best glucosamine for dogs. A potent mix of glucosamine hydrochloride, chondroitin sulfate, and MSM in this popular brand helps keep joints in the best shape. Your dog’s joints need strong cartilage to be comfortable and lubricated, and these key elements work together to achieve just that.

Available in tasty chewable tablets or soft chews, Cosequin makes it easy to support dogs of all sizes. Produced in the USA with ingredients obtained all over the world, it provides reliable, high-quality care. Glucosamine chondroitin in this supplement is great for keeping your dog active and comfortable, whether you’re trying to treat joint pain or keep it from happening in the first place.

PHOTO CREDIT: AMAZON

Why We Love

Contains 600 mg of glucosamine per chew

Has Omega-3 fatty acids

Includes MSM for healthy tissues and muscles

Endorsed by veterinarians

Delicious Flavor

Soft-chew format

But…

Some pet parents report that the soft chews were too hard for their dogs

Keep your furry friend moving with VetIQ Hip & Joint supplements. These tasty chicken-flavored chews are veterinarian-recommended to ease joint stiffness caused by everyday activity. Formulated with 600mg of glucosamine, these supplements help support healthy joint cartilage and flexibility.

Easy to give and packed with benefits, VetIQ Hip & Joint also includes MSM for strong connective tissues. Not only that, but omega-3 fatty acids like DHA and EPA help keep joints lubricated and comfortable for your fur buddy. Made in the USA, these delicious chews make supporting your dog’s joint health a treat they’ll actually enjoy.

Best Plant-based Glucosamine

YuMOVE Hip and Joint Supplement

PHOTO CREDIT: AMAZON

Why We Love

Veterinarian recommended

Scientifically proven

Triple-action formula

Includes antioxidants

Plant-based glucosamine

Suitable for senior dogs

But…

More expensive than some other joint supplements

Supporting your senior dog’s mobility can make a big difference in their quality of life. YuMOVE, the UK’s #1 vet-recommended joint supplement brand, offers a scientifically proven solution. This triple-action formula combines plant-based glucosamine (helping determine the right glucosamine dose for dogs mg/kg is crucial), chondroitin, and hyaluronic acid to support joint structure and cushion.

Antioxidants like vitamins C and E help protect cells. A lot of pet parents say that their dogs can move around better now (after consuming it) and that it’s easier for them to walk and run. While individual results may vary, YuMOVE offers a natural approach to supporting your senior dog’s comfort and quality of life.

Best for Small/Medium Breeds

Wuffes Chewable Dog Hip and Joint Supplement

PHOTO CREDIT: AMAZON

Why We Love

Tailored for small and medium breeds

Scientifically backed ingredients

Improves range of motion

Tasty and easily digestible chews

Prevents joint deterioration

Recommended by veterinarians

But…

May take up to three months to show improvements

Wuffes Hip & Joint Support chews are designed to help your smaller pup or medium-sized buddy live their best life. With compounds like glucosamine, hyaluronic acid, and green-lipped mussel that have been backed by science, these chews can help ease your dog’s joint pain and increase their range of motion.

Joint lubrication, flexibility, and healthy cartilage are all functions that are supported by this supplement. And because it is easily digestible, Wuffes is gentle on sensitive stomachs while delivering effective results. Trusted by veterinarians and pet parents alike, it’s a smart choice for maintaining your dog’s joint health.

PHOTO CREDIT: AMAZON

Why We Love

Specifically designed for senior dogs

Comprehensive ingredients

Soft, chewable treats

Suitable for dogs of all sizes

Provides anti-inflammatory relief

Trusted by vets

But…

Not suitable for younger dogs

Maintaining your dog’s mobility is effortless with Strellalab’s advanced glucosamine chondroitin joint supplement. Designed for senior dogs, this vet-approved formula combines glucosamine, chondroitin, MSM, and hyaluronic acid to support smooth joint movement and reduce inflammation. 

No matter what size dog you have, these tasty chewables will help their joints in many ways. Unlike pills or tablets, these soft chews make supplementation easy and enjoyable for your furry friend. By addressing potential glucosamine for dogs side effects with a focus on quality ingredients, Strellalab helps ensure your senior dog can enjoy a happy and active life.

PHOTO CREDIT: AMAZON

Why We Love

Contains high-quality ingredients like OptiMSM

Available in tasty duck and bacon flavors

Helps maintain healthy cartilage and connective tissue

Includes vitamins C and E

Convenient chewable format

Suitable for multiple breeds

But…

While most dogs love the flavors, some picky eaters might still resist

Zesty Paws Mobility Bites are delicious chews that support your dog’s joint health. The ingredients in these treats are great for your pup’s joints because they contain glucosamine, chondroitin, and OptiMSM, a type of MSM that helps keep their muscles healthy. Plus, with added vitamins C and E, they give your dog’s joints the complete care they deserve, keeping them active and moving freely.

These chews are easy to administer and come in yummy duck and bacon flavors — a treat your dog will love. Remember, while these chews are generally safe, it’s always a good idea to consult with your veterinarian to determine the appropriate dosage and to discuss any potential interactions with other supplements your dog may be taking. 

PHOTO CREDIT: AMAZON

Why We Love

Made with premium, natural ingredients

Results in as little as one month

Tasty bacon flavor

Eco-friendly packaging

Anti-inflammatory benefits

No artificial additives

But…

Some dogs may find the chews a bit large, especially those with small mouths

With visible improvements in just one month, Pet Honesty Hip & Joint Health Soft Chews are a great choice for both proactive and supportive joint health care. Formulated with a Natural Pure Vitality Blend, these delicious bacon-flavored chews combine ingredients like glucosamine, chondroitin, and turmeric to help reduce joint discomfort, support cartilage development, and enhance joint fluid function. The result is improved mobility and flexibility. 



Because this supplement helps your dog’s body’s natural defenses fight inflammation and keep joints healthy, it is usually recommended by vets. It’s important to note that human glucosamine for dogs dosage (in any form) should be avoided — always use dog-specific glucosamine supplements like Pet Honesty’s to ensure your dog’s safety and well-being.

Can Too Much Glucosamine Hurt a Dog?

While generally safe, giving your dog too much glucosamine can have some side effects. Too much may sometimes make your pup sick, causing diarrhea or vomiting. In rare cases, prolonged high doses could strain the liver or kidneys. It’s essential to follow the recommended dosage based on your dog’s weight and size.

Always check a glucosamine for dogs dosage chart or consult your vet to ensure proper administration. Factors like breed, age, and existing health conditions can influence the safe dosage. To get the most out of glucosamine for your dog without any adverse side effects, you should give it to them in moderation.

How We Chose the Best Glucosamine Supplements for Dogs

At DogTime, our experts curated this list of the best Glucosamine supplements for dogs by assessing factors such as high-quality ingredients, easy-to-administer format, whether it has omega fatty acids and antioxidant benefits, and overall price. They further consulted with industry professionals to gain more insight into the top-selling products to bring our readers the clearest view. When you choose one of our recommended products, you can rest assured that you’re making an informed purchase from the best brands available on the market.

FAQ

What time of day should I give my dog glucosamine?

You can give your dog glucosamine at any time of day, but it’s best to give it with a meal to improve absorption and reduce the chance of stomach upset. Just be consistent with the timing each day.

How long does it take for glucosamine to leave a dog’s system?

Glucosamine typically stays in a dog’s system for about 24 to 48 hours. The exact duration can vary based on your dog’s size, metabolism, and dosage. For consistent results, it’s important to follow the recommended dosage.

Should I give my dog supplements in the morning or at night?

You can give your dog supplements either in the morning or at night, depending on what works best for your routine. Consistency is key, so choose a time that’s easy for you to remember each day.

Is glucosamine hard on the liver?

Glucosamine is generally safe for most dogs when given in recommended doses. However, if your dog has liver issues, it’s always best to consult with your vet before starting any supplement to ensure it’s appropriate for their condition.

Can I give my dog human glucosamine chondroitin?

It’s not recommended to give your dog human glucosamine chondroitin, as the dosage and ingredients may differ from dog-specific supplements. Always use products formulated for pets to ensure safety and effectiveness, and consult your vet if unsure.

How much glucosamine for dogs is too much?

The recommended dosage for glucosamine varies depending on your dog’s size and weight. Giving your dog too much glucosamine can lead to side effects like digestive upset. Always follow the recommended dosage on the product label or consult your veterinarian.

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